sexta-feira, 9 de abril de 2010

Evolutionary Theory of Cancer

As Theodosius Dobzhansky famously noted in 1973, “Nothing in biology makes sense except in the light of evolution,” and cancer is no exception to this rule.Our understanding of cancer initiation, progression, treatment, and resistance has advanced considerably by regarding cancer as the product of evolutionary processes. Here we review the literature of mathematical models of cancer evolution and provide a synthesis and discussion of the field.
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09 Evolutionary Theory of Cancer

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